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Drug Used To Fight Tumors in Animals May Be Effective in Treating COVID-19

Scientists using the Advanced Photon Source have discovered that a drug used to fight tumors in animals might be effective against many types of coronaviruses, including SARS-CoV-2. Scientists from the University of Chicago have found that the drug masitinib may be effective in treating COVID-19. The drug, which has undergone several clinical trials for human conditions but has not yet received approval to treat humans, inhibited the replication of SARS-CoV-2, the virus that causes COVID-19, in human cell cultures and in a mouse model, leading to much lower viral loads. “(X-ray crystallography) gave us a strong indication of how this…

Stanford AI Algorithm Solves Structural Biology Challenges

Lead image: A new artificial intelligence algorithm can pick out an RNA molecule’s 3D shape from incorrect shapes. Computational prediction of the structures into which RNAs fold is particularly important – and particularly difficult – because so few structures are known. Credit: Camille L.L. Townshend Stanford machine learning algorithm predicts biological structures more accurately than ever before. Stanford researchers develop machine learning methods that accurately predict the 3D shapes of drug targets and other important biological molecules, even when only limited data is available. Determining the 3D shapes of biological molecules is one of the hardest problems in modern biology…

Greenland Was Actually Green About 55 Million Years Ago. Rapid Global Warming Shows Us What The Future May Hold

Frozen northeast Greenland seems an unlikely place to gain insight into our ever-warming world. Between 50 million and 60 million years ago, however, the region was a different place. Back then Greenland had a subtropical climate befitting of its name. It was host to volcanic activity that restructured the land and ocean connections and drove rapid warming. The abrupt global warming event 56 million years ago, known as the Paleocene-Eocene Thermal Maximum (PETM), is often used as a worrying analog for our current climate crisis. Our research, published Monday (Aug. 23) in Communications Earth and Environment, provides crucial details about the…

NASA GOLD’s Bird’s-Eye Reveals Mysterious Dynamics in Earth’s Interface to Space

Lead image: Processes in Earth’s upper atmosphere create bright swaths of color known as airglow, as seen here in an image taken from the International Space Station. Credit: NASA New research using data from NASA’s Global-scale Observations of the Limb and Disk, or GOLD, mission, has revealed unexpected behavior in the swaths of charged particles that band Earth’s equator – made possibly by GOLD’s long-term global view, the first of its kind for this type of measurement. GOLD is in geostationary orbit, which means it orbits around Earth at the same pace the planet turns and “hovers” over the same…

The 12 Bestselling Techniques To Use Every Day

To be successful in a commercial negotiation, good upstream preparation is essential. To perform, prioritize tasks, target the right people, optimize their prospecting and maximize deal signatures, here is a summary of the best sales techniques that every salesperson should know. To be used without moderation to optimize your sales! 12 essential sales techniques for any salesperson: ABM : targeting your prospect CAB method : impact your commercial discourse BEBEDC : make a good discovery Customer Centric Selling : understanding customer needs SPIN Selling : strengthening active listening skills SPANCO : improve its conversion rate 4C : establish a customer relationship CAP SONCAS : develop an argument BATNA :…